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Journal of Clinical Medicine

The Mixed Tendency in Bipolar Disorder: An Operational Proposal for the Integration of Mixed Episodes in Predominant Polarity

Journal of Clinical Medicine, 2023 · Cited by 5 papers · doi:10.3390/jcm12237398

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What this article backs

• Mixed Episode ↑ Suicide Risk

• Mixed Episode increases Suicide Risk.

In its own words

Our findings revealed that the mixed tendency correlated significantly with early BD type I, lifetime suicide attempts, self-aggressive behaviour, and lifetime number of affective episodes (>5).

Corroborated by

• Illustration V

  Síntomas mixtos en los trastornos del ánimo: una revisión histórica, clínica y terapéutica | Vertex Revista Argentina de Psiquiatría

  Vertex Revista Argentina de Psiquiatría · Jan 10, 2026 High trust

  Backs 3 claims

  • Mixed Episode ↑ Suicide Risk
  • Manic Episode ↔ Mixed Episode
  • Depressive Episode ↔ Mixed Episode

  Read article →
• Illustration J

  Functional brain abnormalities in adolescents and young adults with bipolar depression with mixed features: Insights from resting-state fMRI

  Journal of Psychiatric Research · Sep 3, 2025 High trust

  Backs 1 claim

  • Mixed Episode ↑ Suicide Risk

  Read article →
• Illustration B

  History of suicide attempts in pediatric bipolar disorder: factors associated with increased risk

  Bipolar Disorders · Dec 1, 2005 High trust

  Backs 8 claims

  • Mixed Episode ↑ Suicide Risk
  • Psychosis Risk ↑ Suicide Risk
  • Substance Use ↑ Suicide Risk
  • Anxiety Comorbidity ↑ Suicide Risk
  • Childhood Trauma ↑ Suicide Risk
  • Family History Of Mood Disorder ↑ Suicide Risk
  • Psychiatric Hospitalization ↑ Suicide Risk
  • Bipolar Disorder Severity ↑ Suicide Risk

  Read article →
• Illustration T

  Suicide and Attempted Suicide in Bipolar Disorder: A Systematic Review of Risk Factors

  The Journal of Clinical Psychiatry · Jun 15, 2005 High trust

  Backs 10 claims

  • Previous Suicide Attempt ↑ Suicide Risk
  • Hopelessness ↑ Suicide Risk
  • Family History Of Mood Disorder ↑ Suicide Risk
  • Early Episode Onset ↑ Suicide Risk
  • Depressive Episode ↑ Suicide Risk
  • Bipolar Disorder Severity ↑ Suicide Risk
  • Mixed Episode ↑ Suicide Risk
  • Rapid Cycling ↑ Suicide Risk
  • Anxiety Comorbidity ↑ Suicide Risk
  • Substance Use ↑ Suicide Risk

  Read article →

More from Journal of Clinical Medicine

• Illustration J

  Stabilizing Sleep–Wake Cycles and Social Functioning in Bipolar Disorders: Effect of Interpersonal and Social Rhythm Therapy

  Journal of Clinical Medicine · Jan 29, 2026 High trust

  Backs 2 claims

  • Interpersonal Social Rhythm Therapy ↓ Circadian Rhythm Disruption
  • Interpersonal Social Rhythm Therapy ↓ Functional Impairment

  Read article →