Research maps for complex topics
Turn scattered research into a shared topic map.
Thematic helps teams build shared maps of a topic, connect causes and effects, and turn source material into a focused research workspace.
Ask it once. First findings within the hour. Your full map within 2 business days. The first one's on us.
Cause and effect graph
Bipolar Disorder
Center node
Manic Episode
The anchor of this map (event). Its strongest causes and effects fan out around it.
Causal relationship
Manic Episode → Clang Associations
clanging is a positive formal thought disorder sign - speech driven by sound (rhyme, pun) rather than meaning - and positive FTD scores peak in acute mania, the highest of any diagnostic group on the TALD scale
Causal relationship
Lithium Treatment → Manic Episode
Lithium outperforms placebo in acute mania and roughly halves the risk of manic relapse on maintenance, making it the reference anti-manic mood stabilizer.
Causal relationship
Antipsychotic Treatment → Manic Episode
Second-generation antipsychotics such as cariprazine are first-line for acute bipolar mania, shortening and blunting manic episodes.
Causal relationship
Dopamine Dysregulation → Manic Episode
Converging imaging and pharmacological evidence ties mania to hyperdopaminergia - elevated D2/3 receptor availability and hyperactive reward circuitry - and dopamine-boosting drugs can induce mania.
Causal relationship
Circadian Rhythm Disruption → Manic Episode
A second brain clock rhythm, working in tandem with the sleep-wake cycle, drives alternation between mania and depression
Manic Episode
Where the map converges: 4 causes feed in and 1 effect ripple out.
Evidence
0.56Lithium outperforms placebo in acute mania and roughly halves the risk of manic relapse on maintenance, making it the reference anti-manic mood stabilizer.
Source: strongest evidenced cause link
Node detail
strength 63Clang Associations
Best path: Manic Episode → Clang Associations
Tour tips
FinaleMake any node the center to re-orient the map, then use discover more to grow the promising branches.
Center orientation
Lineage fans out from the selected center.
- Ingest
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Free first map
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Your map file
Three steps. Then one real map.
We map sources, claims, and certainty before we ask who you are.
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1
Ask
Type the question keeping you up at night
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2
We map it
Sources, claims, causes, evidence strength
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3
You explore it
Follow the strongest arrows and share it
- 7 published maps
- 337 cited sources
- 310 claims
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Type the question keeping you up at night, or at least keeping a lot of tabs open.
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Not sure what a map looks like? Here are a few we made earlier.