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Patients who had experienced three or more manic episodes were more impaired in cognitive functions when compared with patients with a history of only one or two episodes.
Cariprazine for Treating Schizophrenia, Mania, Bipolar Depression, and Unipolar Depression: A Review of Its Efficacy - PMC
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Efficacy and safety of lumateperone for bipolar depression and schizophrenia: a systematic review and meta-analysis - PMC
Improving Treatment Adherence in Bipolar Disorder: A Review of Current Psychosocial Treatment Efficacy and Recommendations for Future Treatment Development - PMC
Sleep loss as a trigger of mood episodes in bipolar disorder: individual differences based on diagnostic subtype and gender - PMC
Outcome of single manic episode in bipolar I disorder: a six-month follow-up after hospitalization - PMC