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PubMed Central

Efficacy and safety of lumateperone for bipolar depression and schizophrenia: a systematic review and meta-analysis - PMC

The International Journal of Neuropsychopharmacology, 2024 · Cited by 10 papers · doi:10.1093/ijnp/pyae052

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What this article backs

• Antipsychotic Treatment ↓ Depressive Episode

• Antipsychotic Treatment decreases Depressive Episode.

In its own words

Lumateperone is a novel approved APD by the FDA for treating adults with schizophrenia or bipolar I and II depression, either as monotherapy or in conjunction with lithium or valproate.

Corroborated by

• Illustration B

  Canadian Network for Mood and Anxiety Treatments ( CANMAT ) and International Society for Bipolar Disorders ( ISBD ) 2018 guidelines for the management of patients with bipolar disorder

  Bipolar Disorders · Mar 1, 2018 High trust

  Backs 6 claims

  • Lithium Treatment ↓ Manic Episode
  • Lithium Treatment ↓ Depressive Episode
  • Antipsychotic Treatment ↓ Manic Episode
  • Antipsychotic Treatment ↓ Depressive Episode
  • Antipsychotic Treatment ↓ Relapse Rate
  • Lithium Treatment ↓ Relapse Rate

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