Lithium Treatment decreases Manic Episode.

They pull in opposite directions: more cause, less effect. The map scores it at 73% confidence, weighed from 4 articles.

DecreasesRelation
-Polarity
73%Confidence
variesLag
StrongStrength
ActiveStatus

How it works

Lithium outperforms placebo in acute mania and roughly halves the risk of manic relapse on maintenance, making it the reference anti-manic mood stabilizer.

The evidence

4Backing articles
3Publishers
4Evidence records
Dec 2012–Mar 2018Coverage

Canadian Network for Mood and Anxiety Treatments ( CANMAT ) and International Society for Bipolar Disorders ( ISBD ) 2018 guidelines for the management of patients with bipolar disorder

Bipolar Disorders Mar 1, 2018 High trust
Backs 6 claims
Read article →
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013

Bipolar Disorders Dec 12, 2012 High trust
Backs 3 claims
Read article →
Long-Term Lithium Therapy for Bipolar Disorder: Systematic Review and Meta-Analysis of Randomized Controlled Trials

psychiatryonline.org High trust
Backs 1 claim
- Lithium Treatment Manic Episode
Read article →
pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov High trust
Backs 1 claim
- Lithium Treatment Manic Episode
Read article →

None of these receipts match that. Try a looser word, or .

Where it sits

What feeds it

Nothing upstream on the map yet.

What it drives

Manic Episode increases Clang Associations.
Manic Episode correlates with Mixed Episode.
Manic Episode increases Psychosis Risk.
Manic Episode increases Functional Impairment.
Manic Episode decreases Cognitive Performance.
Manic Episode triggers Depressive Episode.

See it on the live map →