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psychiatryonline.org

Long-Term Lithium Therapy for Bipolar Disorder: Systematic Review and Meta-Analysis of Randomized Controlled Trials

American Journal of Psychiatry, 2004 · Cited by 665 papers · doi:10.1176/appi.ajp.161.2.217

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What this article backs

• Lithium Treatment ↓ Manic Episode

• Lithium Treatment decreases Manic Episode.

In its own words

Lithium was more effective than placebo in preventing all relapses (relative risk=0.65, 95% CI=0.50 to 0.84) and manic relapses (relative risk=0.62, 95% CI=0.40 to 0.95).

Corroborated by

• Illustration B

  Canadian Network for Mood and Anxiety Treatments ( CANMAT ) and International Society for Bipolar Disorders ( ISBD ) 2018 guidelines for the management of patients with bipolar disorder

  Bipolar Disorders · Mar 1, 2018 High trust

  Backs 6 claims

  • Lithium Treatment ↓ Manic Episode
  • Lithium Treatment ↓ Depressive Episode
  • Antipsychotic Treatment ↓ Manic Episode
  • Antipsychotic Treatment ↓ Depressive Episode
  • Antipsychotic Treatment ↓ Relapse Rate
  • Lithium Treatment ↓ Relapse Rate

  Read article →
• Illustration B

  Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013

  Bipolar Disorders · Dec 12, 2012 High trust

  Backs 3 claims

  • Lithium Treatment ↓ Manic Episode
  • Antipsychotic Treatment ↓ Manic Episode
  • Lithium Treatment ↓ Depressive Episode

  Read article →
• Illustration P

  pubmed.ncbi.nlm.nih.gov

  pubmed.ncbi.nlm.nih.gov High trust

  Backs 1 claim

  • Lithium Treatment ↓ Manic Episode

  Read article →