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Eight switched out of depression, and seven were rated as manic or hypomanic; in...

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Eight switched out of depression, and seven were rated as manic or hypomanic; indicating that sleep loss (such as occurs with spontaneous 48-hour sleep-wake cycles) may help to trigger switches from depression to mania.
doi.org · May 1, 1982
The majority of patients experienced one or more consecutive 48-hour sleep-wake cycles (alternate nights with no sleep) when they switched out of depression into mania of hypomania.
doi.org · May 1, 1982

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