Archives of General Psychiatry
A Placebo-Controlled 18-Month Trial of Lamotrigine and Lithium Maintenance Treatment in Recently Manic or Hypomanic Patients With Bipolar I Disorder
What this article backs
- Lithium Treatment Relapse Rate
- Lamotrigine Treatment Relapse Rate
- Lamotrigine Treatment Depressive Episode
- Lithium Treatment Manic Episode
- Lithium Treatment decreases Relapse Rate.
- Lamotrigine Treatment decreases Relapse Rate.
- Lamotrigine Treatment prevents Depressive Episode.
- Lithium Treatment prevents Manic Episode.
In its own words
Both lamotrigine and lithium were superior to placebo at prolonging the time to intervention for any mood episode (lamotrigine vs placebo, P =.02; lithium vs placebo, P =.006).
Lithium was superior to placebo at prolonging the time to a manic, hypomanic, or mixed episode (P =.006).
Lamotrigine was superior to placebo at prolonging the time to a depressive episode (P =.02).
