Nature and Science of Sleep
The role of sleep in bipolar disorder | NSS | Dove Medical Press
What this article backs
- Circadian Rhythm Disruption triggers Depressive Episode.
- Circadian Rhythm Disruption triggers Manic Episode.
In its own words
A convergence of evidence suggests that sleep problems in bipolar disorder result from dysregulation across both process C and process S systems. Biomarkers of depressive episodes include heightened fragmentation of rapid eye movement (REM) sleep, reduced REM latency, increased REM density, and a greater percentage of awakenings.
Biomarkers of manic episodes include reduced REM latency, greater percentage of stage I sleep, increased REM density, discontinuous sleep patterns, shortened total sleep time, and a greater time awake in bed.
