Causal claim

Blood Brain Barrier Antisense Oligonucleotide Cns Distribution

Blood Brain Barrier prevents Antisense Oligonucleotide Cns Distribution.

They pull in opposite directions: more cause, less effect. The map scores it at 44% confidence, weighed from 1 article.

How it works

Size and charge of most oligonucleotides prevent systemic distribution across the blood brain barrier into the CNS.

The evidence

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