Causal claim

Sugar 2 Prime Position Modification Antisense Oligonucleotide Potency

Sugar 2 Prime Position Modification increases Antisense Oligonucleotide Potency.

The two move together: more cause, more effect. The map scores it at 43% confidence, weighed from 1 article.

How it works

2' sugar modifications increase RNA binding affinity, prolonging RNA inhibitory activity and tissue half-life.

The evidence

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