Thematic

Causal claim

Msh3 Somatic Cag Expansion

Msh3 increases Somatic Cag Expansion.

The two move together: more cause, more effect. The map scores it at 42% confidence, weighed from 1 article.

How it works

MSH3 (part of the MutSβ mismatch-repair heterodimer) recognises CAG slip-outs and promotes somatic expansion of the repeat in vulnerable neurons

The evidence

Where it sits

What feeds it

Nothing upstream on the map yet.

What it drives

See it on the live map →