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Sequence Variants in Small CAG Repeat Expansions of the HTT Gene and Disease Onset and Progression in Huntington Disease | Neurology

Neurology, 2025 · Cited by 4 papers · doi:10.1212/wnl.0000000000214404

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What this article backs

• Htt Gene Mutation ⚡ Neurodegeneration

• Htt Gene Mutation triggers Neurodegeneration.

In its own words

Sequence Variants in Small CAG Repeat Expansions of the HTT Gene and Disease Onset and Progression in Huntington Disease

Corroborated by

• Illustration E

  A hitch in the stitch reveals why DNA sequence patterns matter in Huntington’s disease   – HDBuzz

  en.hdbuzz.net · Feb 9, 2026 Standard

  Backs 1 claim

  • Htt Gene Mutation ⚡ Neurodegeneration

  Read article →
• M

  Huntingtin protein arranges cytoskeletal filaments, offering insight into neurodegeneration

  medicalxpress.com · Oct 1, 2025 Standard

  Backs 1 claim

  • Htt Gene Mutation ⚡ Neurodegeneration

  Read article →
• Illustration M

  Nonallele-specific Silencing of Mutant and Wild-type Huntingtin Demonstrates Therapeutic Efficacy in Huntington's Disease Mice

  Molecular Therapy · Feb 24, 2009 High trust

  Backs 4 claims

  • Htt Gene Mutation ⚡ Neurodegeneration
  • Htt Lowering Therapy ↓ Neurodegeneration
  • Htt Lowering Therapy ↑ Motor Coordination
  • Htt Lowering Therapy ↑ Survival

  Read article →