Thematic Pro

Causal claim

Htt Lowering Therapy ↑ Motor Coordination

Htt Lowering Therapy increases Motor Coordination.

The two move together: more cause, more effect. The map scores it at 45% confidence, weighed from 1 article.

• IncreasesRelation
• +Polarity
• 45%Confidence
• weeksLag
• StrongStrength
• ActiveStatus

How it works

Nonallele-specific RNAi cosilencing of wild-type and mutant htt improved motor coordination in HD mice

The evidence

• 1Backing articles
• 1Publishers
• 1Evidence records
• Feb 2009–Feb 2009Coverage

• Illustration M

  Nonallele-specific Silencing of Mutant and Wild-type Huntingtin Demonstrates Therapeutic Efficacy in Huntington's Disease Mice

  Molecular Therapy · Feb 24, 2009 High trust

  Backs 4 claims

  • Htt Gene Mutation ⚡ Neurodegeneration
  • Htt Lowering Therapy ↓ Neurodegeneration
  • Htt Lowering Therapy ↑ Motor Coordination
  • Htt Lowering Therapy ↑ Survival

  Read article →

Where it sits

See it on the live map →