Causal claim

Sky 0515 Mutant Huntingtin Protein

Sky 0515 decreases Mutant Huntingtin Protein.

They pull in opposite directions: more cause, less effect. The map scores it at 43% confidence, weighed from 2 articles.

How it works

dose-dependent knockdown of mutant huntingtin protein observed in Phase 1 clinical update

The evidence

Where it sits

What feeds it

Nothing upstream on the map yet.

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