Causal claim

Mutant Huntingtin Protein Tdp 43 Pathology

Mutant Huntingtin Protein triggers Tdp 43 Pathology.

The two move together: more cause, more effect. The map scores it at 7% confidence, weighed from 1 article.

How it works

mutant huntingtin protein interacts with or disrupts TDP-43 function, linking HD biology to ALS-associated protein aggregation

The evidence

Where it sits

What it drives

Nothing downstream on the map yet.

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