Causal claim

Antisense Oligonucleotide Mutant Huntingtin Protein

Antisense Oligonucleotide decreases Mutant Huntingtin Protein.

They pull in opposite directions: more cause, less effect. The map scores it at 80% confidence, weighed from 6 articles.

How it works

ASOs lower mutant huntingtin expression in Huntington mouse models

The evidence

Where it sits

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