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Pharmacological treatment for bipolar mania: a systematic review and network meta-analysis of double-blind randomized controlled trials - PMC

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Antipsychotics, carbamazepine, lithium, tamoxifen, and valproate were effective for acute mania, with recent guidelines recommending various second generation antipsychotics, lithium, and valproate as first-line monotherapy for adults with acute mania.
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